SCHEMBL10458653

SCHEMBL10458653

FCCOCc1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
AGXT P21549 2/20 0.52
MAOB P27338 5/20 0.47
LOXL2 Q9Y4K0 1/20 0.46
APP P05067 7/20 0.43
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1965032 0.84 IDO1 (0.50) IDO1AGXTMAOBAPP
SCHEMBL7888039 0.83 IDO1 (0.64) IDO1AGXTMAOBLOXL2APP
Ethylene Glycol SCHEMBL5570418 0.83 IDO1 (0.48) IDO1AGXTMAOBAPP
Hydrochloric Acid SCHEMBL8205628 0.83 IDO1 (0.57) IDO1AGXTMAOBLOXL2APP
SCHEMBL10853302 0.81 IDO1 (0.47) IDO1AGXTMAOBAPP
SCHEMBL10458632 0.80 IDO1 (0.50) IDO1AGXTMAOBAPPTAAR1
SCHEMBL10458365 0.80 AGXT (0.50) IDO1AGXTMAOBAPPTAAR1
SCHEMBL10458623 0.80 IDO1 (0.50) IDO1MAOBAPPTAAR1
SCHEMBL5981060 0.80 IDO1 (0.50) IDO1AGXTMAOBLOXL2APP
SCHEMBL15565620 0.80 APP (0.42) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960884-A Insecticides, nematocides, pesticides and miticides FMC CORPORATION (US) 1990-10-02 US claimed