Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.58 |
| ▸ | CA9 | Q16790 | 9/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA6 | P23280 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934537 | 0.97 | CA12 (0.62) | CA12CA9CA1CA6CA7 | |
| SCHEMBL8934524 | 0.85 | CA12 (0.65) | CA12CA9CA1CA6CA7 | |
| SCHEMBL24045405 | 0.80 | CA12 (0.82) | CA12CA9CA1CA6CA7 | |
| SCHEMBL8934483 | 0.80 | AR (0.61) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL17299895 | 0.78 | CA12 (0.53) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086715 | 0.78 | CA12 (0.65) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086623 | 0.78 | CA12 (0.77) | CA12CA9CA1CA6CA7 | |
| SCHEMBL31086804 | 0.78 | CA12 (0.77) | CA12CA9CA1CA6CA7 | |
| SCHEMBL12679315 | 0.77 | CA12 (0.64) | CA12CA9CA1CA6CA7 | |
| SCHEMBL14356146 | 0.77 | CA12 (0.64) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942242-A | ANTICHOLESTEROL AGENTS | KOJIMA TADAO (JP) | 1990-07-17 | — | — | US | disclosed |
| US-4798838-A | ANTICOAGULANTS, ANTICHOLESTEROL AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-17 | — | — | US | disclosed |
| US-4795753-A | Certain pyridyl or imidazol-1-yl-alkyleneoxy-(or amino)phenoxy-alkanoates having lipid lowering activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4794113-A | ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |