Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 18/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459915 | 0.95 | PTAFR (0.79) | PTAFRLMNATBXAS1 | |
| SCHEMBL10459973 | 0.88 | PTAFR (0.70) | PTAFRLMNATBXAS1 | |
| SCHEMBL10459972 | 0.88 | PTAFR (0.70) | PTAFRLMNATBXAS1 | |
| SCHEMBL10459831 | 0.88 | PTAFR (0.79) | PTAFRLMNATBXAS1 | |
| SCHEMBL10459832 | 0.88 | PTAFR (0.79) | PTAFRLMNATBXAS1 | |
| SCHEMBL10458207 | 0.87 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10458209 | 0.87 | PTAFR (1.00) | PTAFR | |
| SCHEMBL10459200 | 0.84 | PTAFR (0.78) | PTAFR | |
| SCHEMBL10459916 | 0.84 | PTAFR (0.77) | PTAFRLMNATBXAS1 | |
| SCHEMBL10459917 | 0.84 | PTAFR (0.77) | PTAFRLMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |