Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460327 | 0.94 | SLC29A1 (0.82) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| SCHEMBL10459777 | 0.91 | SLC29A1 (0.78) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Hydrochloric Acid SCHEMBL9808242 | 0.90 | SLC29A1 (0.86) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| SCHEMBL10460559 | 0.88 | SLC29A1 (0.73) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Hydrochloric Acid SCHEMBL10678583 | 0.88 | SLC29A1 (0.81) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Hydrochloric Acid SCHEMBL7801696 | 0.88 | SLC29A1 (0.72) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| SCHEMBL9808198 | 0.87 | SLC29A1 (0.71) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Mioflazine SCHEMBL119416 | 0.86 | SLC29A1 (0.68) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Mioflazine SCHEMBL124029 | 0.86 | SLC29A1 (0.70) | SLC29A1KCNH2HTR2ADRD3SLC6A3 | |
| Mioflazine SCHEMBL8675598 | 0.85 | SLC29A1 (0.69) | SLC29A1KCNH2HTR2ADRD3SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968684-A | N-ARYL-PIPERAZINEALKANAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-06 | — | — | US | claimed |