Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160092 | 1.00 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL30657796 | 0.98 | SMN1; SMN2 (0.74) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL15266076 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL5776419 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL7402531 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| Bromide SCHEMBL8568783 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL14156164 | 0.98 | SMN1; SMN2 (0.74) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL11641810 | 0.98 | SMN1; SMN2 (0.74) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| Iodide SCHEMBL8569085 | 0.98 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL481360 | 0.96 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3286 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079861-A | Advanced industrialized tetrahydrocarbazole preparation process | — | 2026-05-26 | — | — | CN | claimed |
| CN-122010958-A | Synthesis method of natural product Pyrroloazocine indole alkaloid skeleton | 中国医学科学院药物研究所 | 2026-05-12 | — | — | CN | claimed |
| EP-4711356-A1 | TETRAHYDROCARBAZOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Nain Biotech (Hangzhou) Co., Ltd. (CN) | 2026-03-18 | — | — | EP | claimed |
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | claimed |
| CN-119912432-A | Method for synthesizing carbazole derivative by using water as reaction solvent through multicomponent one-pot method | 天津力生制药股份有限公司 | 2025-05-02 | — | — | CN | claimed |
| US-20250129092-A1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2025-04-24 | — | — | US | claimed |
| US-20250066667-A1 | Nonlinear Optical Chromophores Having Tetrahydrocarbazole Donor Groups, Lyotropic Compositions Containing the Same, and Methods of Poling Such Compositions | LIGHTWAVE LOGIC, INC. (US) | 2025-02-27 | — | — | US | claimed |
| US-12226398-B2 | FABP4 as a therapeutic target in skin diseases | TICURE LTD. (IL) | 2025-02-18 | — | — | US | claimed |
| CN-119350225-A | Synthesis method of hydrogen storage material N-ethyl carbazole | 连云港海迪化工科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| US-12173217-B2 | Nonlinear optical chromophores having tetrahydrocarbazole donor groups, lyotropic compositions containing the same, and methods of poling such compositions | LIGHTWAVE LOGIC, INC. (US) | 2024-12-24 | — | — | US | claimed |
| US-4618614-A | Method of treating psychosis using tetrahydrocarbazole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-21 | — | — | US | claimed |
| US-4547576-A | Tetrahydrocarbazole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-15 | — | — | US | claimed |
| US-4525588-A | FOR HEAT AND PRESSURE SENSITIVE RECORDING MATERIALS | CIBA GEIGY CORPORATION (US) | 1985-06-25 | — | — | US | claimed |
| EP-0006208-B1 | PROCESS FOR THE PREPARATION OF CARBAZOLES AND AN INTERMEDIATE THEREFOR | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-12-02 | — | — | EP | claimed |
| US-4292323-A | Phenyl-1,2,3,4-tetrahydrocarbazoles and use thereof | SCHERING CORPORATION (US) | 1981-09-29 | — | — | US | claimed |
| US-4057640-A | ANTIINFLAMMATORY | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | claimed |
| US-3976779-A | 1,2,3,4-Tetrahydro-carbazole compounds and β-adrenergic compositions | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-08-24 | — | — | US | claimed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | claimed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | claimed |
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | claimed |