Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 8/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 8/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 7/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 7/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10460426 | 0.98 | CHRM3 (0.97) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL10651354 | 0.90 | CHRM3 (0.97) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL10656906 | 0.88 | CHRM3 (1.00) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL10459676 | 0.83 | CHRM3 (1.00) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL10460362 | 0.83 | CHRM3 (1.00) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL10460271 | 0.81 | CHRM3 (0.97) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL10460503 | 0.81 | CHRM3 (0.97) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL10460418 | 0.80 | CHRM3 (0.82) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL24355248 | 0.79 | HTR2C (0.77) | CHRM3CHRM5CHRM1CHRM2CHRM4 | |
| SCHEMBL10460548 | 0.78 | CHRM3 (0.75) | CHRM3CHRM5CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960769-A | Nervous system disorders | H. LUNDBECK A/S (DK) | 1990-10-02 | — | — | US | disclosed |