Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 1/20 | 0.34 |
| ▸ | SAT1 | P21673 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176504 | 0.71 | SAT1 (0.39) | SAT1TDP1 | |
| SCHEMBL8259142 | 0.71 | — | — | |
| SCHEMBL24774557 | 0.68 | JAK2 (0.33) | LIPASAT1 | |
| SCHEMBL5501993 | 0.67 | CNR2 (0.32) | LIPAPDK1PDK2PDK3PDK4 | |
| SCHEMBL6009077 | 0.67 | CNR2 (0.32) | LIPAPDK1PDK2PDK3PDK4 | |
| SCHEMBL12543828 | 0.67 | SAT1 (0.32) | SAT1TDP1 | |
| SCHEMBL14768807 | 0.67 | SAT1 (0.38) | SAT1TDP1 | |
| SCHEMBL13999478 | 0.67 | SAT1 (0.38) | SAT1TDP1 | |
| SCHEMBL13999522 | 0.67 | SAT1 (0.38) | SAT1TDP1 | |
| SCHEMBL13999524 | 0.67 | SAT1 (0.38) | SAT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275091-A1 | Pharmaceutical compositions comprising adsorbates of an amorphous drug | Pfizer Products Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| EP-1404302-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING ADSORBATES OF AMORPHOUS DRUG | PFIZER PROD INC (US) | 2010-11-03 | — | — | EP | disclosed |