Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.59 |
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463885 | 0.94 | TBXA2R (0.72) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10460235 | 0.91 | MEN1 (0.73) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9754552 | 0.89 | MEN1 (0.84) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9331678 | 0.88 | MEN1 (0.73) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10462666 | 0.85 | TBXA2R (0.60) | TBXA2RMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL9129895 | 0.85 | MEN1 (0.74) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10462121 | 0.85 | TBXA2R (0.60) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9127854 | 0.85 | MEN1 (0.68) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9129125 | 0.84 | MEN1 (0.72) | TBXA2RMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL9661163 | 0.83 | TBXA2R (0.74) | TBXA2RMEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |