Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RPA1 | P27694 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462719 | 0.99 | MAP4K4 (0.42) | MAP4K4SMN1; SMN2PPP1CANPC1RAB9A | |
| SCHEMBL10463696 | 0.86 | HPGD (0.51) | SMN1; SMN2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL10462718 | 0.86 | DHODH (0.39) | MAP4K4SMN1; SMN2PPP1CAMAPTKDM4E | |
| SCHEMBL10463383 | 0.85 | USP2 (0.42) | MAP4K4SMN1; SMN2PPP1CANPC1RAB9A | |
| SCHEMBL10596774 | 0.85 | ABCB1 (0.40) | SMN1; SMN2NPC1RAB9ANOTUMKDM4E | |
| SCHEMBL10460461 | 0.85 | MEN1 (0.38) | L3MBTL1HPGDDHODHMEN1GAA | |
| SCHEMBL10460246 | 0.85 | HPGD (0.50) | SMN1; SMN2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL10597520 | 0.85 | EGLN1 (0.43) | MAPTNOTUMKDM4ELMNAHPGD | |
| SCHEMBL10462369 | 0.84 | USP2 (0.41) | MAP4K4SMN1; SMN2PPP1CANPC1RAB9A | |
| SCHEMBL10460282 | 0.84 | MEN1 (0.37) | L3MBTL1HPGDDHODHMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4964896-A | GAMETOCIDES | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4936904-A | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants | MONSANTO TECHNOLOGY LLC | 1990-06-26 | — | — | US | disclosed |
| EP-0127313-B1 | THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-07-19 | — | — | EP | disclosed |
| US-4714492-A | HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0127313-A1 | The production of haploid seed, of doubled haploids and of homozygous plant lines therefrom | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-12-05 | — | — | EP | disclosed |