Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464368 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10359816 | 0.87 | TDP1 (0.43) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10464786 | 0.87 | TDP1 (0.43) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10359644 | 0.86 | TDP1 (0.42) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10346737 | 0.84 | TDP1 (0.45) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10463894 | 0.83 | FFAR1 (0.43) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10346795 | 0.82 | FFAR1 (0.42) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10346797 | 0.82 | FFAR1 (0.42) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL9559057 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL10346768 | 0.81 | TDP1 (0.39) | KDM4EALDH1A1HTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904677-A | Certain phenoxy- or benzyl substituted pyridylmethyloxy-alkenes having insecticidal properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4812483-A | PESTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0227369-A1 | Insecticidal alkenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |