Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10465607 | 1.00 | TDP1 (0.42) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10603869 | 1.00 | TDP1 (0.42) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10465616 | 0.94 | CACNA1B (0.42) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10465617 | 0.94 | CACNA1B (0.42) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10466417 | 0.92 | TDP1 (0.41) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10466419 | 0.92 | TDP1 (0.41) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10645924 | 0.92 | TDP1 (0.40) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9481547 | 0.92 | TDP1 (0.53) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9481554 | 0.92 | TDP1 (0.53) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10645132 | 0.91 | TDP1 (0.40) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925948-A | CEPHALOSPORIN ANTIBIOTIC CHEMICAL INTERMEDIATES | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0055465-B1 | 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4596829-A | Pharmaceuticals | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4438113-A | 7-Acylaminocephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0055465-A2 | 7-Acylaminocephalosporanic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-07 | — | — | EP | disclosed |