Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878023 | 0.91 | KLKB1 (0.35) | — | |
| SCHEMBL9877285 | 0.88 | KDM4E (0.47) | FAAHHDAC1KDM4EALDH1A1LMNA | |
| SCHEMBL10077158 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1LMNASMN1; SMN2MGLL | |
| SCHEMBL9876997 | 0.66 | MAPK14 (0.55) | KDM4EALDH1A1LMNASMN1; SMN2TP53 | |
| SCHEMBL19370631 | 0.66 | DAO (0.50) | FAAHKDM4EALDH1A1LMNAGAA | |
| SCHEMBL11175776 | 0.65 | KCNH2 (0.44) | ALDH1A1SMN1; SMN2TDP1HPGDHTT | |
| SCHEMBL2893839 | 0.65 | F2 (0.46) | ALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL15923547 | 0.65 | KMT2A (0.60) | FAAHKDM4EALDH1A1LMNAGAA | |
| SCHEMBL9877955 | 0.64 | HDAC8 (0.49) | FAAHKDM4EALDH1A1LMNAGAA | |
| SCHEMBL14282017 | 0.63 | KCNH2 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4977188-A | Hydroamic acid derivatives | BURROUGHS WELLCOME CO. (US) | 1990-12-11 | — | — | US | disclosed |