SCHEMBL10466403

SCHEMBL10466403

CC(C)(C)OC(=O)CO/N=C(/C(=O)O)c1nc(NC=O)sc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9482610 1.00
SCHEMBL9482619 1.00
SCHEMBL11086084 0.85 MEN1 (0.32)
SCHEMBL11086082 0.85 MEN1 (0.32)
SCHEMBL10466816 0.85 GCK (0.34)
SCHEMBL10466815 0.85 GCK (0.34)
SCHEMBL10467218 0.85
SCHEMBL10467220 0.85
SCHEMBL11274266 0.85
SCHEMBL11274263 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925948-A CEPHALOSPORIN ANTIBIOTIC CHEMICAL INTERMEDIATES FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US disclosed
EP-0055465-B1 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-23 EP disclosed
EP-0057422-B1 NEW CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-10-12 EP disclosed
EP-0191507-A2 New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-08-20 EP disclosed
US-4596829-A Pharmaceuticals FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-06-24 US disclosed
US-4452851-A BACTERICIDES, ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-06-05 US disclosed
US-4438113-A 7-Acylaminocephalosporanic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-03-20 US disclosed
EP-0057422-A2 New cephem compounds, processes for preparation thereof and pharmaceutical composition containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-08-11 EP disclosed
EP-0055465-A2 7-Acylaminocephalosporanic acid derivatives and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-07-07 EP disclosed