SCHEMBL10467003

SCHEMBL10467003

C=CCON=C(C(=O)O)c1nc(NC(=O)C(F)(F)F)sc1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10467001 1.00 GCK (0.32) GCK
SCHEMBL10817948 0.84
SCHEMBL10465535 0.84
SCHEMBL10465536 0.84
SCHEMBL10466457 0.82 GCK (0.32) GCK
SCHEMBL10466455 0.82 GCK (0.32) GCK
SCHEMBL10466816 0.81 GCK (0.34) GCK
SCHEMBL10466815 0.81 GCK (0.34) GCK
SCHEMBL10971051 0.79 GAA (0.42)
SCHEMBL10971052 0.79 GAA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925948-A CEPHALOSPORIN ANTIBIOTIC CHEMICAL INTERMEDIATES FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US disclosed
EP-0055465-B1 7-ACYLAMINOCEPHALOSPORANIC ACID DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-08-23 EP disclosed
EP-0055466-B1 CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR STARTING COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-05-06 EP disclosed
US-4596829-A Pharmaceuticals FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-06-24 US disclosed
US-4438113-A 7-Acylaminocephalosporanic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-03-20 US disclosed
US-4427677-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-01-24 US disclosed
EP-0055466-A2 Cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-07-07 EP disclosed
EP-0055465-A2 7-Acylaminocephalosporanic acid derivatives and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-07-07 EP disclosed