Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468079 | 0.93 | HTR2A (0.48) | HTR2AHTR2CHTR2BADRA1APDE4B | |
| SCHEMBL10469055 | 0.81 | HTR2A (0.50) | HTR2AHTR2CHTR2BPDE4B | |
| SCHEMBL29791619 | 0.78 | HTR2C (0.46) | HTR2AHTR2CHTR2BADRA1APDE4B | |
| SCHEMBL18440155 | 0.78 | HTR2C (0.46) | HTR2AHTR2CHTR2BADRA1APDE4B | |
| Hydrochloric Acid SCHEMBL29960911 | 0.77 | HTR2C (0.42) | HTR2AHTR2CHTR2BADRA1APDE4B | |
| Hydrochloric Acid SCHEMBL29960934 | 0.76 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL10468072 | 0.74 | — | — | |
| SCHEMBL10469000 | 0.72 | HTR2C (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL9312201 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL29959697 | 0.70 | HTR2A (0.43) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |