Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500666 | 1.00 | GAA (0.53) | GAAKMT2AHDAC8CACNA1GPLA2G10 | |
| SCHEMBL12065126 | 1.00 | GAA (0.53) | GAAKMT2AHDAC8CACNA1GPLA2G10 | |
| SCHEMBL10468606 | 0.89 | KMT2A (0.56) | GAAKMT2AHDAC8CACNA1G | |
| SCHEMBL10468604 | 0.89 | KMT2A (0.56) | GAAKMT2AHDAC8CACNA1G | |
| SCHEMBL10467251 | 0.83 | HDAC8 (0.45) | GAAHDAC8PLA2G10PLA2G5HRH3 | |
| SCHEMBL10467651 | 0.83 | CXCR4 (0.47) | GAAKMT2A | |
| SCHEMBL10467652 | 0.83 | CXCR4 (0.47) | GAAKMT2A | |
| SCHEMBL15178973 | 0.83 | GAA (0.46) | GAAKMT2AHDAC8CACNA1G | |
| SCHEMBL24608268 | 0.82 | HDAC8 (0.53) | GAAKMT2AHDAC8CACNA1G | |
| SCHEMBL1226583 | 0.82 | HDAC8 (0.56) | GAAHDAC8PLA2G10PLA2G5HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4940709-A | PLATELET ACTIVATING FACTOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0181152-B1 | PIPERAZINE COMPOUND AS PAF-ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4806538-A | ANTICOAGULANT, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-21 | — | — | US | disclosed |
| EP-0181152-A1 | Piperazine compound as PAF-antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |