Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450554 | 0.87 | MEN1 (0.43) | MEN1KMT2AKDM4C | |
| SCHEMBL3704510 | 0.86 | MEN1 (0.42) | MEN1KMT2AKDM4C | |
| SCHEMBL3705231 | 0.85 | MEN1 (0.44) | MEN1KMT2AKDM4C | |
| SCHEMBL6151098 | 0.85 | MEN1 (0.33) | MEN1KMT2AKDM4CGRM5WEE1 | |
| SCHEMBL24450592 | 0.85 | MEN1 (0.44) | MEN1KMT2AKDM4C | |
| SCHEMBL3715148 | 0.85 | MEN1 (0.44) | MEN1KMT2AKDM4C | |
| SCHEMBL10576592 | 0.83 | MEN1 (0.38) | MEN1KMT2AKDM4CGRM5 | |
| SCHEMBL5857211 | 0.83 | MEN1 (0.34) | MEN1KMT2AKDM4CGRM5WEE1 | |
| SCHEMBL6151292 | 0.83 | MEN1 (0.36) | MEN1KMT2AKDM4CGRM5WEE1 | |
| SCHEMBL10578693 | 0.83 | CHRM2 (0.34) | MEN1KMT2AKDM4CGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939169-A | 1,4-naphthalenediol and 1,4-hydroquinone derivatives | THE UPJOHN COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4871868-A | FROM AN ORGANIC HALIDE OR AN ARYL SULFONATE AND AN ALKALI METAL ACETYLIDE, 1,3-DIALKYL-2-IMIDAZOLIDINONE PROMOTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4851586-A | LIPOXYGENASE AND LEUKOTRIENE INHIBITORS, ANTIINFLAMMATORY, ANTISECRETORY | THE UPJOHN COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0284237-A1 | Production of substituted acetylenic compounds | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0246245-A1 | 1,4-NAPHTHALENEDIOL AND 1,4-HYDROQUINONE DERIVATIVES | THE UPJOHN COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| WO-1987001698-A2 | 1,4-NAPHTHALENEDIOL AND 1,4-HYDROQUINONE DERIVATIVES | THE UPJOHN COMPANY (US) | 1987-03-26 | — | — | WO | disclosed |
| EP-0038160-B1 | QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-19 | — | — | EP | disclosed |
| US-4393075-A | SLOW-REACTING-SUBSTANCE OF ANAPHYLAXIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| EP-0038160-A1 | Quinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-10-21 | — | — | EP | disclosed |