Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GSDMD | P57764 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 4/20 | 0.36 |
| ▸ | PHGDH | O43175 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469200 | 1.00 | CA12 (0.37) | CA12CA1CA2CA9EHMT2 | |
| SCHEMBL12677906 | 0.73 | EHMT2 (0.42) | CA12CA1CA2CA9EHMT2 | |
| SCHEMBL8373881 | 0.73 | NPC1 (0.44) | CA12CA1CA9LMNATAS1R3 | |
| SCHEMBL8881036 | 0.73 | NPC1 (0.44) | CA12CA1CA9LMNATAS1R3 | |
| SCHEMBL1583600 | 0.72 | — | — | |
| SCHEMBL8038735 | 0.70 | CA12 (0.50) | CA12CA1CA2CA9MGLL | |
| SCHEMBL7882834 | 0.69 | — | — | |
| SCHEMBL7880933 | 0.69 | — | — | |
| SCHEMBL7880936 | 0.69 | — | — | |
| SCHEMBL7882832 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963275-A | POLYOLEFIN MODIFIED BY AN UNSATURATED ANHYDRIDE, THE REACTION PRODUCT OF A POLYAMINE AND ACRYLIC COMPOUND AND A LACTONE OR POLYLACTONE; OIL ADDITIVES | EXXON CHEMICAL PATENTS INC. (US) | 1990-10-16 | — | — | US | disclosed |