Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 4/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CEL | P19835 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469196 | 0.79 | CYP1B1 (0.65) | CYP1B1CDK4CCND1STSCYP1A1 | |
| SCHEMBL10470036 | 0.79 | CYP1B1 (0.65) | CYP1B1CDK4CCND1STSCYP1A1 | |
| SCHEMBL27683996 | 0.79 | CYP1B1 (0.44) | CYP1B1CDK4CCND1PTGER1STS | |
| SCHEMBL10469157 | 0.77 | CYP1B1 (0.63) | CYP1B1STSCYP1A1CYP1A2SIGMAR1 | |
| SCHEMBL25451382 | 0.75 | CYP1B1 (0.50) | CYP1B1CDK4CCND1CSNK2A2CSNK2B | |
| SCHEMBL27798757 | 0.74 | STS (0.60) | CYP1B1STSSIGMAR1 | |
| SCHEMBL27798671 | 0.72 | STS (0.59) | CYP1B1STSSIGMAR1 | |
| SCHEMBL25177490 | 0.72 | CYP1B1 (0.47) | CYP1B1CDK4CCND1STSCYP1A1 | |
| SCHEMBL25451398 | 0.72 | CYP1B1 (0.47) | CYP1B1CDK4CCND1PTGER1STS | |
| SCHEMBL30994804 | 0.72 | CYP1B1 (0.47) | CYP1B1CDK4CCND1STSCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904690-A | Chromone derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0283761-A1 | Chromone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |