SCHEMBL10471663

SCHEMBL10471663

CCC(C(=O)O)(c1ccc(N(C)C)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.48
ALDH1A1 P00352 5/20 0.44
HPGD P15428 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 1/20 0.41
HDAC1 Q13547 4/20 0.41
HDAC3 O15379 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10473215 0.89 MAPT (0.50) SLC2A1ALDH1A1HPGDMAPTRAB9A
SCHEMBL10471778 0.86 SLC2A1 (0.46) SLC2A1ALDH1A1HPGDMAPTRAB9A
SCHEMBL10473985 0.84 MEN1 (0.47) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL4192907 0.79 ESR1 (0.54) ALDH1A1HPGDLMNATSHRHSD17B10
SCHEMBL396913 0.78 CHRM2 (0.51) ALDH1A1MAPTRAB9ALMNATSHR
SCHEMBL10651642 0.77 SLC2A1 (0.44) SLC2A1ALDH1A1HPGDMAPTRAB9A
SCHEMBL4246611 0.77 CYP1A2 (0.44) ALDH1A1MAPTRAB9ANPC1GAA
SCHEMBL27815694 0.76 SLC2A1 (0.43) SLC2A1ALDH1A1HPGDMAPTRAB9A
SCHEMBL10473429 0.75 SLC2A1 (0.54) SLC2A1ALDH1A1HPGDMAPTRAB9A
SCHEMBL4678223 0.75 SLC2A1 (0.54) SLC2A1ALDH1A1HPGDMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4898941-A Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-02-06 US disclosed
EP-0257591-A2 Process for preparing diphenylalkene derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-03-02 EP disclosed