Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474343 | 1.00 | DHODH (0.57) | DHODHMAPTGAANPC1RAB9A | |
| SCHEMBL13885846 | 0.93 | DHODH (0.58) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL10474353 | 0.89 | DHODH (0.53) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL10474352 | 0.89 | DHODH (0.53) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL10474560 | 0.88 | DHODH (0.52) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL10474559 | 0.88 | DHODH (0.52) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL3565253 | 0.86 | DHODH (0.58) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL13885851 | 0.86 | DHODH (0.58) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL3565256 | 0.86 | DHODH (0.58) | DHODHMAPTGAANPSR1KDM4E | |
| SCHEMBL3569446 | 0.85 | MAPT (0.61) | DHODHMAPTGAANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959363-A | HERPES VIRUS | STERLING DRUG INC. (US) | 1990-09-25 | — | — | US | disclosed |