Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391385 | 0.90 | PPARA (0.69) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10635423 | 0.89 | PPARA (0.60) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10635269 | 0.88 | PPARA (0.59) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10473704 | 0.86 | PPARA (0.65) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10474998 | 0.86 | NR1H4 (0.70) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10641305 | 0.85 | PPARA (0.54) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10641301 | 0.85 | PPARA (0.54) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL21389589 | 0.84 | MEN1 (0.67) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10641653 | 0.84 | PPARA (0.65) | PPARACYP2C9CYP1A2TSHRCYP2C8 | |
| SCHEMBL10474698 | 0.83 | PPARA (0.61) | PPARACYP2C9CYP1A2TSHRCYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882357-A | ANTICHOLESTEROL AGENT; INCREASES HIGH DENSITY LIPOPROTEINS | WARNER-LAMBERT COMPANY (US) | 1989-11-21 | — | — | US | claimed |
| US-4975456-A | For inhibiting intestinal absorption of cholesterol and increasing high density lipoprotein | WARNER-LAMBERT COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
| US-4882357-A | ANTICHOLESTEROL AGENT; INCREASES HIGH DENSITY LIPOPROTEINS | WARNER-LAMBERT COMPANY (US) | 1989-11-21 | — | — | US | disclosed |