Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.49 |
| ▸ | HTR2B | P41595 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 7/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10476310 | 0.91 | HTR2C (0.41) | HTR2CHTR2BHTR2ACYP2D6MLNR | |
| SCHEMBL10476250 | 0.89 | HTR2A (0.47) | HTR2CHTR2BHTR2ACYP2D6PNMT | |
| SCHEMBL10228938 | 0.87 | HTR2A (0.49) | HTR2CHTR2BHTR2ACYP2D6PNMT | |
| SCHEMBL10228933 | 0.86 | HTR2C (0.48) | HTR2CHTR2BHTR2ACYP2D6MLNR | |
| SCHEMBL10476234 | 0.86 | HTR2C (0.50) | HTR2CHTR2BHTR2AMLNRPNMT | |
| SCHEMBL10229002 | 0.86 | HTR2C (0.40) | HTR2CHTR2BHTR2ACYP2D6PNMT | |
| SCHEMBL10476286 | 0.85 | HTR2C (0.47) | HTR2CHTR2BHTR2ACYP2D6MLNR | |
| Hydrochloric Acid SCHEMBL508526 | 0.85 | HTR2C (0.39) | HTR2CHTR2BHTR2ACYP2D6PNMT | |
| SCHEMBL10229012 | 0.85 | HTR2A (0.39) | HTR2CHTR2BHTR2ACYP2D6PNMT | |
| SCHEMBL10476290 | 0.84 | HTR2C (0.43) | HTR2CHTR2BHTR2APNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | claimed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | claimed |