SCHEMBL10477178

SCHEMBL10477178

CCCCC[C@H]1CC[C@H](c2ccc(C(=O)Cc3ccc([N+](=O)[O-])cc3)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.45
LMNA P02545 2/20 0.45
PGR P06401 1/20 0.42
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPK1 P28482 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
GSK3B P49841 1/20 0.39
SPHK1 Q9NYA1 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10477180 1.00 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10347815 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10477101 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10477103 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10347807 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10347806 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10347817 0.99 CYP2C9 (0.46) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10477199 0.97 CYP2C9 (0.47) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10477198 0.97 CYP2C9 (0.47) CYP2C9ALDH1A1MAPTLMNAPGR
SCHEMBL10348254 0.92 CYP2C9 (0.55) CYP2C9ALDH1A1MAPTLMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4849130-A ISOTHIOCYANATES WOJSKOWA AKADEMIA TECHNICZNA (PL) 1989-07-18 US disclosed