Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477335 | 0.83 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL10477333 | 0.82 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL10477318 | 0.82 | CYP19A1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL10477356 | 0.82 | CYP19A1 (0.43) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL10515148 | 0.81 | CYP19A1 (0.54) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL9398517 | 0.78 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL8954696 | 0.77 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL8954579 | 0.77 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| Hydrochloric Acid SCHEMBL9399211 | 0.76 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| Bromide SCHEMBL10477473 | 0.76 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826862-A | Anthelminthic [(5(6) (1H-azole-1-ylmethyl)benzimidazole]carbamates | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-05-02 | — | — | US | disclosed |