Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23886361 | 1.00 | CHRNA7 (0.39) | CHRNA7ACHETDP1CA2CA1 | |
| SCHEMBL25248787 | 1.00 | CHRNA7 (0.39) | CHRNA7ACHETDP1CA2CA1 | |
| Hydrochloric Acid SCHEMBL25259928 | 0.98 | CHRNA7 (0.38) | CHRNA7ACHETDP1CA2CA1 | |
| Hydrochloric Acid SCHEMBL25202953 | 0.98 | CHRNA7 (0.38) | CHRNA7ACHETDP1CA2CA1 | |
| Hydrochloric Acid SCHEMBL25202951 | 0.98 | CHRNA7 (0.38) | CHRNA7ACHETDP1CA2CA1 | |
| SCHEMBL20644490 | 0.81 | PDE2A (0.41) | PDE2AESR1ESR2KIF11LMNA | |
| SCHEMBL13591013 | 0.80 | CHRNA7 (0.42) | CHRNA7ACHETDP1CA2CA1 | |
| SCHEMBL296872 | 0.78 | IDO1 (0.44) | CA2CA1CA9PDE2AESR1 | |
| SCHEMBL14305986 | 0.78 | IDO1 (0.44) | CA2CA1CA9PDE2AESR1 | |
| Hydrochloric Acid SCHEMBL25187772 | 0.76 | IDO1 (0.46) | PDE2AESR1ESR2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12247233-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2025-03-11 | — | — | US | claimed |
| US-20220290197-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2022-09-15 | — | — | US | claimed |
| EP-2446026-B1 | TRANSAMINASE REACTIONS | CODEXIS INC (US) | 2017-08-09 | — | — | EP | claimed |
| US-9434968-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2016-09-06 | — | — | US | claimed |
| US-20150079640-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2015-03-19 | — | — | US | claimed |
| US-8921079-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2014-12-30 | — | — | US | claimed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | claimed |
| US-12247233-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2025-03-11 | — | — | US | disclosed |
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-4126848-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2023-02-08 | — | — | EP | disclosed |
| US-20220290197-A1 | TRANSAMINASE REACTIONS | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2022-09-15 | — | — | US | disclosed |
| US-8921079-B2 | Transaminase reactions | CODEXIS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190085-A1 | Transaminase Reactions | CODEXIS, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2446026-A1 | TRANSAMINASE REACTIONS | Codexis, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |
| WO-2011005477-A1 | TRANSAMINASE REACTIONS | CODEXIS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| WO-2011005477-A1 | TRANSAMINASE REACTIONS | CODEXIS, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150981-A1 | N-HETEROARYLALKYL-2-(HETEROCYCLYL AND HETEROCYCLYLMETHYL) ACETAMIDE DERIVATIVES AS SSTR4 AGONISTS | SSTR4, SSTR3, SSTR5 | CHRNA7 483/4885ACHE 2358/4885TDP1 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.