SCHEMBL10477652

SCHEMBL10477652

C=CC(=O)OCCCCCCCCCCOc1ccc(C(=O)Oc2ccc(-c3ccc(C(=O)OCC(C)CC)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
NPC1 O15118 3/20 0.45
LMNA P02545 2/20 0.45
NFKB1 P19838 2/20 0.45
NFKB2 Q00653 2/20 0.45
RELA Q04206 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RARB P10826 4/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
PRSS1 P07477 1/20 0.41
ACR P10323 1/20 0.41
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408498 1.00 MAPT (0.47) MAPTNPC1LMNANFKB1NFKB2
SCHEMBL10408336 1.00 MAPT (0.47) MAPTNPC1LMNANFKB1NFKB2
SCHEMBL10409029 1.00 MAPT (0.47) MAPTNPC1LMNANFKB1NFKB2
SCHEMBL10408337 1.00 MAPT (0.47) MAPTNPC1LMNANFKB1NFKB2
SCHEMBL10408125 1.00 MAPT (0.47) MAPTNPC1LMNANFKB1NFKB2
SCHEMBL9489638 0.97 MAPT (0.50) MAPTCYP3A4RARBALDH1A1HPGD
SCHEMBL9488682 0.97 MAPT (0.50) MAPTCYP3A4RARBALDH1A1HPGD
SCHEMBL9151915 0.97 MAPT (0.50) MAPTCYP3A4RARBALDH1A1HPGD
SCHEMBL9455770 0.97 MAPT (0.50) MAPTCYP3A4RARBALDH1A1HPGD
SCHEMBL10333528 0.97 MAPT (0.50) MAPTCYP3A4RARBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4844835-A FAST RESPONSE, DISPLAYING MOTION PICTURES IDENITSU KOSAN CO., LTD. (JP) 1989-07-04 US disclosed
EP-0228703-A2 Ferroelectric liquid crystal polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-07-15 EP disclosed