Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10480057 | 1.00 | BACE1 (0.50) | BACE1MMECTSCFOLH1NAALAD2 | |
| SCHEMBL29630420 | 0.93 | BACE1 (0.52) | BACE1FOLH1NAALAD2RIMKLACTSD | |
| Ammonia Solution, Strong SCHEMBL29404690 | 0.92 | BACE1 (0.52) | BACE1CTSCFOLH1NAALAD2RIMKLA | |
| SCHEMBL30590545 | 0.90 | FOLH1 (0.50) | BACE1CTSCFOLH1NAALAD2RIMKLA | |
| SCHEMBL30148936 | 0.89 | MME (0.46) | BACE1MME | |
| SCHEMBL29777812 | 0.88 | DPP4 (0.50) | BACE1MMEFOLH1NAALAD2RIMKLA | |
| SCHEMBL31211777 | 0.88 | BACE1 (0.47) | BACE1CTSCFOLH1NAALAD2RIMKLA | |
| SCHEMBL29714767 | 0.87 | FOLH1 (0.53) | BACE1CTSCFOLH1NAALAD2RIMKLA | |
| SCHEMBL11049992 | 0.87 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL30777857 | 0.86 | BACE1 (0.45) | BACE1FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888414-A | FOR RAPID DEACTIVATION OR MONITORING OF CIRCULATING BLOOD INSULIN | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0286147-A2 | Insulin-binding peptides and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1988-10-12 | — | — | EP | disclosed |