Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211993 | 0.81 | HDAC1 (0.41) | RECQLALDH1A1TDP1TSHR | |
| SCHEMBL11691872 | 0.78 | RECQL (0.45) | RECQLALDH1A1TDP1TSHR | |
| SCHEMBL890709 | 0.77 | CHRM1 (0.40) | RECQLTDP1 | |
| SCHEMBL13978753 | 0.77 | RECQL (0.36) | RECQLALDH1A1TDP1 | |
| SCHEMBL5022363 | 0.75 | CHRM1 (0.39) | RECQLTDP1 | |
| SCHEMBL10500021 | 0.75 | CA1 (0.37) | RECQL | |
| SCHEMBL5013300 | 0.75 | CHRM1 (0.39) | RECQLTDP1 | |
| SCHEMBL5014288 | 0.75 | CHRM1 (0.39) | RECQLTDP1 | |
| SCHEMBL6631114 | 0.75 | RECQL (0.35) | RECQLTDP1 | |
| SCHEMBL5014260 | 0.75 | CHRM1 (0.39) | RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101638383-B | Quinoline as well as pharmaceutical composition and use thereof | UNIV PEKING FOUNDER GROUP CO | 2013-07-10 | — | — | CN | disclosed |
| CN-101638383-A | Quinoline as well as pharmaceutical composition and use thereof | FOUNDER GROUP | 2010-02-03 | — | — | CN | disclosed |
| CN-1264824-C | Quinazoline derivatives | MITSUBISHI PHARMA CORP (JP) | 2006-07-19 | — | — | CN | disclosed |
| CN-1492860-A | Quinazoline derivatives | ������ҩ��ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| US-4801694-A | Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety | CIBA-GEIGY CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |