SCHEMBL10480484

SCHEMBL10480484

C=CCOC(=O)N1C(=O)N(c2ccc(C(C)=NO)cc2)C(=O)C1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 9/20 0.43
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
MAPT P10636 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
NPC1 O15118 1/20 0.38
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FAAH O00519 3/20 0.32
MGLL Q99685 1/20 0.32
GAA P10253 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10480482 1.00 CA9 (0.43) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480463 0.84 CA9 (0.39) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480461 0.84 CA9 (0.39) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480554 0.83 CA9 (0.41) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480557 0.83 CA9 (0.41) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480496 0.77 CA9 (0.41) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480494 0.77 CA9 (0.41) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480492 0.71 CA9 (0.44) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480521 0.67 CA9 (0.49) CA9ALDH1A1MEN1KMT2ACA1
SCHEMBL10480526 0.67 CA9 (0.49) CA9ALDH1A1MEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4868061-A ADDITION POLYMERS, ULTRAVIOLET RADIATION STABILIZERS THE STANDARD OIL COMPANY (US) 1989-09-19 US disclosed