Methacrylic Acid

Methacrylic Acid

SCHEMBL10482185

C=C(C)C(=O)O.C=C(C)C(=O)OCCCCCCCCCCCCCC.C=CC(=O)OCCCCCCCCCCCCCC.C=CC(=O)OCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.71
HPGD P15428 1/20 0.60
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 1/20 0.56
HCAR2 Q8TDS4 3/20 0.50
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.42
NAAA Q02083 1/20 0.41
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
EPHX1 P07099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7730831 0.99 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4HCAR2
Methacrylic Acid SCHEMBL10477469 0.99 TSHR (0.69) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL9242062 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL9517492 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL7198242 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL8425793 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL12469797 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL9361594 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL6887082 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL9624268 0.95 TSHR (0.77) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4795577-A MODIFIED ISOCYANATOALKYL ACRYLATE COPOLYMERS TEXACO INC. (US) 1989-01-03 US disclosed