SCHEMBL10482248

SCHEMBL10482248

CCCCCCCCCOc1ccccc1C(SCCC(=O)O)SCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 20/20 1.00
CYSLTR1 Q9Y271 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482137 1.00 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10557303 0.87 CYSLTR2 (0.77) CYSLTR2CYSLTR1
SCHEMBL10482240 0.86 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL9559987 0.85 CYSLTR2 (0.73) CYSLTR2CYSLTR1
SCHEMBL10482177 0.84 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10482299 0.83 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10482309 0.82 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10482315 0.82 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10482211 0.82 CYSLTR2 (1.00) CYSLTR2CYSLTR1
SCHEMBL10482094 0.80 CYSLTR2 (1.00) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4730005-A DITHIA-ALKANEDIOIC ACIDS SMITHKLINE BECKMAN CORPORATION (US) 1988-03-08 US claimed
EP-0168902-A1 Leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-01-22 EP claimed
US-4871771-A PHENYL SUBSTITUTED-DITHIA-ALKANEDIOIC ACIDS SMITHKLINE BECKMAN CORPORATION (US) 1989-10-03 US disclosed
EP-0327306-A2 Leukotriene B4 antagonists SMITHKLINE BEECHAM CORPORATION (US) 1989-08-09 EP disclosed
US-4730005-A DITHIA-ALKANEDIOIC ACIDS SMITHKLINE BECKMAN CORPORATION (US) 1988-03-08 US disclosed
EP-0168902-B1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BECKMAN CORPORATION (US) 1987-09-30 EP disclosed
EP-0168902-A1 Leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-01-22 EP disclosed