SCHEMBL1048245

SCHEMBL1048245

C[Si](C)(C)OC=C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3077174 0.90
SCHEMBL3089026 0.84
SCHEMBL3089023 0.84
SCHEMBL4963502 0.78
SCHEMBL11340986 0.77
SCHEMBL13139166 0.74
SCHEMBL13139168 0.74
SCHEMBL3083600 0.74
SCHEMBL3083601 0.74
SCHEMBL11497922 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11133530-B2 Electrolyte formulations for electrochemical cells containing a silicon electrode WILDCAT DISCOVERY TECHNOLOGIES, INC. (US) 2021-09-28 US claimed
CN-111172548-A Preparation method of super-hydrophobic air-permeable window screen and super-hydrophobic air-permeable window screen 成都斯棱德新材料科技有限公司 2020-05-19 CN claimed
US-20190260079-A1 Electrolyte Formulations for Electrochemical Cells Containing a Silicon Electrode HSBC VENTURES USA INC. 2019-08-22 US claimed
US-20180069265-A1 ELECTROLYTE FORMULATIONS FOR ELECTROCHEMICAL CELLS CONTAINING A SILICON ELECTRODE WILDCAT DISCOVERY TECHNOLOGIES, INC. 2018-03-08 US claimed
EP-0043594-B1 1,1,2-TRIS-TRIMETHYLSILYLOXYETHYLENE AND PROCESS FOR ITS PREPARATION AMERICAN CYANAMID COMPANY (US) 1983-05-11 EP claimed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
US-20240343720-A1 AAK1 INHIBITOR AND USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2024-10-17 US disclosed
US-20240300892-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2024-09-12 US disclosed
EP-4371980-A1 AAK1 INHIBITOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-05-22 EP disclosed
CN-117715899-A AAK1 inhibitors and uses thereof 西藏海思科制药有限公司 2024-03-15 CN disclosed
WO-2023284838-A1 AAK1 INHIBITOR AND USE THEREOF 四川海思科制药有限公司 2023-01-19 WO disclosed
EP-4092012-A1 PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER AMGEN INC. (US) 2022-11-23 EP disclosed
US-4227011-A 15-Deoxy-16-hydroxy-16-chloromethyl or bromomethyl prostaglandins of the E and F series AMERICAN CYANAMID COMPANY (US) 1980-10-07 US disclosed
EP-0015056-A1 1-Hydroxymethyl-1-oxo-prostane derivatives of the E, A and F series AMERICAN CYANAMID COMPANY (US) 1980-09-03 EP disclosed
US-4212969-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1980-07-15 US disclosed
US-4202822-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1980-05-13 US disclosed
US-4197245-A 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series AMERICAN CYANAMID COMPANY (US) 1980-04-08 US disclosed
US-4172839-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1979-10-30 US disclosed
US-4170597-A 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series AMERICAN CYANAMID COMPANY (US) 1979-10-09 US disclosed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 EP disclosed