⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424152 | 0.82 | — | — | |
| SCHEMBL1532636 | 0.76 | — | — | |
| SCHEMBL8310537 | 0.73 | — | — | |
| SCHEMBL2977203 | 0.67 | — | — | |
| SCHEMBL16623259 | 0.64 | — | — | |
| SCHEMBL8902145 | 0.64 | — | — | |
| SCHEMBL14279743 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3108499 | 0.61 | — | — | |
| SCHEMBL2562996 | 0.60 | — | — | |
| 1,2-Dichloroethane SCHEMBL4584447 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294208-B2 | Bendamustine derivatives and related compounds, and medical use thereof in cancer therapy | SYNBIAS PHARMA AG (CH) | 2019-05-21 | — | — | US | claimed |
| CN-109384730-A | 1- { 3- [p- double-(2- chloroethyl) amido] phenylpropyl alcohol amido } formyl -5-fluor-uracil and preparation and application | 南京友怡医药科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| EP-2861564-B1 | BENDAMUSTINE DERIVATIVES AND RELATED COMPOUNDS, AND MEDICAL USE THEREOF FOR CANCER THERAPY | SCHICKANEDER HELMUT (DE) | 2018-08-08 | — | — | EP | claimed |
| US-20170313663-A1 | Bendamustine Derivatives and Related Compounds, and Medical Use Thereof in Cancer Therapy | Schickaneder, Helmut (DE) | 2017-11-02 | — | — | US | claimed |
| WO-2015091827-A1 | BENDAMUSTINE DERIVATIVES AND RELATED COMPOUNDS | SCHICKANEDER HELMUT (DE) | 2015-06-25 | — | — | WO | claimed |
| EP-2886536-A1 | Bendamustine derivatives as anti-proliferative agents | Schickaneder, Helmut (DE) | 2015-06-24 | — | — | EP | claimed |
| US-20150152066-A1 | BENDAMUSTINE DERIVATIVES AND RELATED COMPOUNDS, AND MEDICAL USE THEREOF IN CANCER THERAPY | HELMUT SCHICKANEDER (DE) | 2015-06-04 | — | — | US | claimed |
| EP-2861564-A1 | BENDAMUSTINE DERIVATIVES AND RELATED COMPOUNDS, AND MEDICAL USE THEREOF CANCER THERAPY | Schickaneder, Helmut (DE) | 2015-04-22 | — | — | EP | claimed |
| WO-2013189847-A1 | BENDAMUSTINE DERIVATIVES AND RELATED COMPOUNDS, AND MEDICAL USE THEREOF CANCER THERAPY | SCHICKANEDER HELMUT (DE) | 2013-12-27 | — | — | WO | claimed |
| US-6984634-B2 | Bile-acid conjugates for providing sustained systemic concentrations of drugs | XENOPORT, INC. (US) | 2006-01-10 | — | — | US | claimed |
| US-5969133-A | Bioreductive cytotoxic agents | SHIONGI BIORESEARCH CORP. (US) | 1999-10-19 | — | — | US | claimed |
| EP-0433393-B1 | TREATMENT OF DAMAGED BONE MARROW AND DOSAGE UNITS THEREFOR | UNIV ROCHESTER (US) | 1995-03-15 | — | — | EP | claimed |
| EP-0278337-B1 | AGENTS TO CONTROL PLANT-MITES ON THE BASIS OF AZOMETHINES OF 2,3-DIAMINOMALEIC-ACID NITRILE | BAYER AG (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0262188-B1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF | ROUSSEL-UCLAF (FR) | 1990-11-14 | — | — | EP | claimed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | claimed |
| US-4921872-A | Acaricidal agents based on azomethines of 2,3-diaminomaleic acid nitrile | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | claimed |
| EP-0364819-A2 | LHRH analogs | The Administrators of The Tulane Educational Fund (US) | 1990-04-25 | — | — | EP | claimed |
| EP-0278337-A1 | Agents to control plant-mites on the basis of azomethines of 2,3-diaminomaleic-acid nitrile | BAYER AG (DE) | 1988-08-17 | — | — | EP | claimed |
| US-4132436-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1979-01-02 | — | — | US | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |