Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30784987 | 0.89 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11757124 | 0.89 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30784980 | 0.89 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14869439 | 0.83 | GAA (0.71) | GAASMN1; SMN2 | |
| SCHEMBL2458049 | 0.82 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10483467 | 0.78 | RAD52 (0.54) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10483507 | 0.78 | MEN1 (0.57) | MEN1KMT2AALDH1A1LTA4HCYP1A2 | |
| SCHEMBL10483449 | 0.76 | NPSR1 (0.59) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12245487 | 0.75 | GAA (0.49) | KMT2AKDM4EPKMGAACYP1A2 | |
| SCHEMBL1694966 | 0.75 | MEN1 (0.57) | MEN1KMT2AALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | claimed |