Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | ESRRG | P62508 | 8/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | ESRRA | P11474 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10484096 | 1.00 | ESR1 (0.56) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484167 | 0.95 | ESR1 (0.48) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484445 | 0.95 | ESR1 (0.48) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484033 | 0.93 | ESR1 (0.64) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484030 | 0.93 | ESR1 (0.64) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484027 | 0.93 | ESR1 (0.64) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484038 | 0.91 | ESRRG (0.60) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484022 | 0.91 | ESRRG (0.60) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484242 | 0.91 | ESRRG (0.60) | ESR1ESRRGESR2MAPTHTR6 | |
| SCHEMBL10484042 | 0.91 | ESRRG (0.60) | ESR1ESRRGESR2MAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806685-A | EXERTS VARIOUS EFFECTS ON ENDOCRINOUS SYSTEM OF RATS; INHIBITS GROWTH OF MAMMARY TUMORS | GYOGYSZERKUTATO INTEEZET/PHARMACEUTICAL RESEARCH INSTITUTE (HU) | 1989-02-21 | — | — | US | disclosed |