Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 6/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crisnatol SCHEMBL3883 | 0.92 | SLC2A1 (0.61) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| Crisnatol SCHEMBL6257042 | 0.88 | SLC2A1 (0.52) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| Crisnatol SCHEMBL15990 | 0.88 | SLC2A1 (0.52) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| Crisnatol SCHEMBL10484286 | 0.87 | SLC2A1 (0.51) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| Crisnatol SCHEMBL10811378 | 0.87 | SLC2A1 (0.53) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| SCHEMBL10484174 | 0.85 | SLC2A1 (0.46) | SLC2A1HPRT1CA2 | |
| SCHEMBL10484271 | 0.83 | SLC2A1 (0.46) | SLC2A1HPRT1ALDH1A1MAPTHPGD | |
| SCHEMBL10484205 | 0.82 | SLC2A1 (0.60) | SLC2A1CYP1A2 | |
| SCHEMBL9538875 | 0.82 | SLC2A1 (0.67) | SLC2A1 | |
| SCHEMBL8673861 | 0.81 | SLC2A1 (0.50) | SLC2A1HPRT1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829090-A | SECONDARY AMINES, ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-05-09 | — | — | US | disclosed |
| US-4810727-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1989-03-07 | — | — | US | disclosed |
| US-4719048-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719046-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0125702-B1 | POLYCYCLIC AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-08-12 | — | — | EP | disclosed |
| EP-0125702-A2 | Polycyclic aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-21 | — | — | EP | disclosed |