SCHEMBL10484175

SCHEMBL10484175

COCC(C)(CO)NCc1cc2c3ccccc3ccc2c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.44
HPRT1 P00492 4/20 0.34
NPBWR1 P48145 1/20 0.34
KMT2A Q03164 1/20 0.34
MCHR1 Q99705 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX12 P18054 1/20 0.33
HIF1A Q16665 1/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CD274 Q9NZQ7 1/20 0.32
CCR5 P51681 1/20 0.32
ATM Q13315 1/20 0.32
MTNR1A P48039 2/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10484306 0.99 SLC2A1 (0.43) SLC2A1HPRT1NPBWR1KMT2AMCHR1
SCHEMBL10547740 0.91 SLC2A1 (0.47) SLC2A1NPBWR1KMT2AMCHR1ALDH1A1
Hydrochloric Acid SCHEMBL10546808 0.90 SLC2A1 (0.46) SLC2A1NPBWR1KMT2AMCHR1ALDH1A1
Crisnatol SCHEMBL6257042 0.90 SLC2A1 (0.52) SLC2A1HPRT1NPBWR1KMT2AMCHR1
Crisnatol SCHEMBL15990 0.90 SLC2A1 (0.52) SLC2A1HPRT1NPBWR1KMT2AMCHR1
Crisnatol SCHEMBL10484286 0.89 SLC2A1 (0.51) SLC2A1HPRT1NPBWR1KMT2AMCHR1
SCHEMBL8673861 0.85 SLC2A1 (0.50) SLC2A1HPRT1NPBWR1KMT2AMCHR1
SCHEMBL10484271 0.85 SLC2A1 (0.46) SLC2A1HPRT1NPBWR1KMT2AMCHR1
Crisnatol SCHEMBL3883 0.84 SLC2A1 (0.61) SLC2A1HPRT1ALDH1A1
SCHEMBL10484386 0.83 SLC2A1 (0.42) SLC2A1HPRT1KMT2AALDH1A1MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0125702-B1 POLYCYCLIC AROMATIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1987-08-12 EP claimed
EP-0125702-A2 Polycyclic aromatic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-21 EP claimed
US-4829090-A SECONDARY AMINES, ANTITUMOR BURROUGHS WELLCOME CO. (US) 1989-05-09 US disclosed
US-4810727-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1989-03-07 US disclosed
US-4719048-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
US-4719046-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
EP-0125702-B1 POLYCYCLIC AROMATIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1987-08-12 EP disclosed
EP-0125702-A2 Polycyclic aromatic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-21 EP disclosed