Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668019 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC2A1KDM4CLPAR3 | |
| SCHEMBL21667954 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC2A1KDM4CLPAR3 | |
| SCHEMBL8459105 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC2A1KDM4CLPAR3 | |
| SCHEMBL16264036 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC2A1KDM4CLPAR3 | |
| SCHEMBL9732197 | 0.98 | MEN1 (0.45) | MEN1KMT2ASLC2A1KDM4CLPAR3 | |
| SCHEMBL10486622 | 0.95 | MEN1 (0.45) | MEN1KMT2ASLC2A1KDM4CL3MBTL1 | |
| SCHEMBL14363514 | 0.95 | MEN1 (0.45) | MEN1KMT2ASLC2A1KDM4CL3MBTL1 | |
| SCHEMBL20429037 | 0.90 | MEN1 (0.40) | MEN1KMT2ASLC2A1KDM4CL3MBTL1 | |
| SCHEMBL11917953 | 0.89 | MEN1 (0.43) | MEN1KMT2ASLC2A1KDM4CL3MBTL1 | |
| SCHEMBL19331641 | 0.88 | MEN1 (0.41) | MEN1KMT2ASLC2A1KDM4CL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833157-A | ANTIULCER AGENTS | MILES INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4415592-A | ANTISECRETORY AND HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4370348-A | USING A PROSTAGLANDIN DERIVATIVE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-01-25 | — | — | US | disclosed |
| US-4331688-A | Therapeutic method for inhibiting gastric secretion by administration of 15-deoxy-16-hydroxy prostaglandins | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4275224-A | BRONCHODIALATORS AND ANTI-GASTRIC SECRETION AGENTS | MILES LABORATORIES, INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4132738-A | BRONCHODILATORS, ANTISECRETORY AGENTS | MILES LABORATORIES, INC. (US) | 1979-01-02 | — | — | US | disclosed |