SCHEMBL10486372

SCHEMBL10486372

CCCCCC1CCC1CCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ALDH1A1 P00352 2/20 0.46
ALOX5 P09917 1/20 0.45
CYP1A2 P05177 4/20 0.42
TSHR P16473 2/20 0.41
THRB P10828 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
S1PR2 O95136 1/20 0.35
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
S1PR5 Q9H228 1/20 0.35
LMNA P02545 1/20 0.35
GBA1 P04062 3/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11662768 0.97 EPHX1 (0.52) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL11659426 0.97 EPHX1 (0.52) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL28485961 0.88 CYP1A2 (0.50) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL8791144 0.88 EPHX1 (0.44) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29904852 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29455101 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL28380195 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29385123 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL4004983 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL28358906 0.86 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4885395-A FROM HYDROXY-, ALKOXY-, OR CARBOXYKETONE; ACIDIC CATALYST BASF AKTIENGSELLSCHAFT (DE) 1989-12-05 US disclosed
US-4874899-A CONVERTING METHYLENE DIOXOLANONES OVER ZEOLITE CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1989-10-17 US disclosed
US-4866210-A DEHYDRATION, HYDROGENATION USING AN ACID CATALYST BASF AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed
US-4088583-A WATER, GAS, FOAMING AGENT, EROSION AND CORROSION INHIBITOR, CARBOXYALKYL CELLULOSE ETHER OR POLYALKYLENE OXIDE POLYMER UNION OIL COMPANY OF CALIFORNIA (US) 1978-05-09 US disclosed
US-4035426-A Diarylcyclobutanes MEAD JOHNSON & COMPANY (US) 1977-07-12 US disclosed
US-3939196-A Diarylcyclobutanes MEAD JOHNSON & COMPANY (US) 1976-02-17 US disclosed