⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486248 | 0.93 | CYP2C19 (0.33) | — | |
| SCHEMBL11647642 | 0.76 | CYP2C19 (0.33) | — | |
| SCHEMBL8356265 | 0.75 | — | — | |
| SCHEMBL10486222 | 0.75 | CYP1A2 (0.41) | — | |
| SCHEMBL22697008 | 0.70 | — | — | |
| SCHEMBL252753 | 0.69 | — | — | |
| SCHEMBL9253791 | 0.69 | — | — | |
| SCHEMBL8383850 | 0.68 | — | — | |
| SCHEMBL11824468 | 0.68 | — | — | |
| SCHEMBL22776090 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833157-A | ANTIULCER AGENTS | MILES INC. (US) | 1989-05-23 | — | — | US | disclosed |
| US-4742080-A | Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters | MILES LABORATORIES, INC. (US) | 1988-05-03 | — | — | US | disclosed |
| US-4415592-A | ANTISECRETORY AND HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4331688-A | Therapeutic method for inhibiting gastric secretion by administration of 15-deoxy-16-hydroxy prostaglandins | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4275224-A | BRONCHODIALATORS AND ANTI-GASTRIC SECRETION AGENTS | MILES LABORATORIES, INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4132738-A | BRONCHODILATORS, ANTISECRETORY AGENTS | MILES LABORATORIES, INC. (US) | 1979-01-02 | — | — | US | disclosed |