Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504194 | 0.96 | TSHR (0.44) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL27798854 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL4647014 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL29028814 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL2801984 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL23174294 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL7901796 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL2771038 | 0.93 | TSHR (0.42) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| SCHEMBL330109 | 0.90 | TSHR (0.40) | TSHRADRA2AADRA1AALDH1A1HSD17B10 | |
| Ethylene Glycol SCHEMBL27279388 | 0.87 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804529-A | Use of specific relaxation agents for organs or pathologies for modifying the contrasts in medical imaging by nuclear magnetic resonance | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1989-02-14 | — | — | US | disclosed |