Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | ESR1 | P03372 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424760 | 0.86 | ELANE (1.00) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL27810901 | 0.83 | ELANE (0.75) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL45119 | 0.82 | ELANE (0.72) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| Benzene SCHEMBL28089483 | 0.82 | ELANE (0.72) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL9799566 | 0.82 | ELANE (0.72) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL10414510 | 0.81 | KMT2A (0.68) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL717516 | 0.81 | ELANE (0.76) | ELANEKMT2AESR1SMN1; SMN2MAPT | |
| SCHEMBL5690655 | 0.80 | KMT2A (0.72) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| SCHEMBL8467278 | 0.80 | ELANE (0.70) | ELANEKMT2AESR1SMN1; SMN2HIF1A | |
| Ammonia Solution, Strong SCHEMBL22042017 | 0.80 | ELANE (0.70) | ELANEKMT2AESR1SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1013052-A | — | — | None | — | — | JP | disclosed |
| JP-1013052-A | — | — | None | — | — | JP | disclosed |
| JP-S6413052-A | PRODUCTION OF ((1-PHENYLETHENYL) PHENYL) PROPIONIC ACID AND/OR ITS ESTER | NIPPON PETROCHEMICALS CO LTD | 1989-01-17 | — | — | JP | disclosed |
| JP-S6413052-A | PRODUCTION OF ((1-PHENYLETHENYL) PHENYL) PROPIONIC ACID AND/OR ITS ESTER | NIPPON PETROCHEMICALS CO LTD | 1989-01-17 | — | — | JP | disclosed |