Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493777 | 1.00 | ACE (0.48) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10487559 | 1.00 | ACE (0.48) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10866456 | 0.92 | ACE (0.51) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL8284096 | 0.84 | ACE (0.48) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10493796 | 0.84 | ACE (0.49) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10487574 | 0.83 | ACE (0.47) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10487581 | 0.83 | ACE (0.47) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10604351 | 0.81 | ACE (0.51) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10493733 | 0.81 | ACE (0.51) | ACELMNAABCB11MEN1KMT2A | |
| SCHEMBL10756676 | 0.81 | ACE (0.51) | ACELMNAABCB11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |