SCHEMBL1048764

SCHEMBL1048764

NC(O)Cc1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.64
SLC6A2 P23975 2/20 0.64
SLC7A5 Q01650 1/20 0.57
ESR1 P03372 5/20 0.50
ESR2 Q92731 5/20 0.50
ABAT P80404 1/20 0.50
OPRK1 P41145 1/20 0.47
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTR3A P46098 1/20 0.46
BACE1 P56817 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
IDO1 P14902 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21632218 1.00 TAAR1 (0.64) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL21357615 1.00 TAAR1 (0.64) TAAR1SLC6A2SLC7A5ESR1ESR2
Hydrochloric Acid SCHEMBL10616562 0.98 TAAR1 (0.61) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL6575823 0.89 TAAR1 (0.48) TAAR1SLC6A2SLC7A5
SCHEMBL8014472 0.82 TAAR1 (0.67) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL15951398 0.82 TAAR1 (0.67) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL25085818 0.81 TAAR1 (0.59) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL1255738 0.81 TAAR1 (0.59) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL44609 0.81 TAAR1 (0.59) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL13367316 0.81 TAAR1 (0.59) TAAR1SLC6A2SLC7A5ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768554-B Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2024-06-07 CN claimed
CN-116768554-A Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2023-09-19 CN claimed
CN-116376014-A Organic Janus nanosheet stable water-based carbon dioxide foam and preparation method and application thereof 中国石油大学(北京) 2023-07-04 CN claimed
CN-115872367-A Layered structure MoTe 2 /C nanoflower, preparation method and application thereof 陕西科技大学 2023-03-31 CN claimed
CN-109957103-B Special bidentate phosphonic acid water reducing agent for medium-low slump concrete and preparation method thereof 江苏苏博特新材料股份有限公司 2022-04-22 CN claimed
CN-109957103-A A kind of dedicated bidentate type phosphonic acid base water-reducing agent of middle low-slump concrete and preparation method thereof 江苏苏博特新材料股份有限公司 2019-07-02 CN claimed
US-20100143322-A1 USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE PLT PATENT & LICENCE TRADING LTD., C/O THE B-NET (GB) 2010-06-10 US claimed
US-6093805-A AGLYCON COMPOUNDS HAVING HYDROXY, MERCAPTO, OR CARBOXY GROUP AND LINKED TO MONO- AND DISACCHARIDES HAVING 2,3-DIDEOXY-ALPHA-D-ERYTHRO-HEX-2-ENOPYRANOSIDE MOIETY; BETTER PHARMACOLOGICAL PROPERTIES INCLUDING WATER SOLUBILITY THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2000-07-25 US claimed
JP-63005069-A None JP disclosed
CN-116768554-B Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2024-06-07 CN disclosed
CN-116768554-B Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2024-06-07 CN disclosed
WO-2024107708-A1 TAAR RECEPTOR AGONISTS FOR SEXUAL DYSFUNCTION ReJoy (US) 2024-05-23 WO disclosed
CN-116768554-A Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2023-09-19 CN disclosed
CN-116768554-A Superfine mineral admixture self-compacting high-performance concrete and preparation method thereof 盐城市福奇混凝土有限公司 2023-09-19 CN disclosed
JP-S635069-A PRODUCTION OF N-(4-HYDROXYSTYRYL)BENZAMIDE SHISEIDO CO LTD 1988-01-11 JP disclosed
EP-0182279-A1 Process for the optical resolution of racemic mixtures of alpha-naphtyl-propionic acids ALFA WASSERMANN S.p.A. (IT) 1986-05-28 EP disclosed
EP-0143371-A1 Process for the optical resolution of racemic mixtures of alpha-naphthyl-propionic acids Alfa Chemicals Italiana S.r.l. (IT) 1985-06-05 EP disclosed
US-4148908-A BRONCHODILATORS MEAD JOHNSON & COMPANY (US) 1979-04-10 US disclosed
US-4055658-A BETA-ADRENERGIC STIMULANTS, BRONCHIAL MEAD JOHNSON & COMPANY (US) 1977-10-25 US disclosed
US-3818101-A METHODS FOR IMPROVING THE FEED INTAKE OF MEAT PRODUCING ANIMALS SMITHKLINE BECKMAN CORPORATION 1974-06-18 US disclosed