Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603597 | 1.00 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL11612777 | 0.88 | MEN1 (0.44) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL32688604 | 0.88 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL32688743 | 0.85 | MEN1 (0.47) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL32688826 | 0.85 | MEN1 (0.47) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL1527314 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL189532 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL1785153 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL20573107 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL20573120 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868337-A | Optically active borinic esters and ketones | ALDRICH-BORANES, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4795821-A | Optically active borinic esters and ketones | ALDRICH-BORANES, INC. (US) | 1989-01-03 | — | — | US | disclosed |