SCHEMBL10489558

SCHEMBL10489558

BrCN1C=Cc2ccccc2C1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.48
PARP1 P09874 1/20 0.33
HSD17B3 P37058 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL4225369 0.98 HDAC3 (0.47) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL28774659 0.85 HDAC3 (0.52) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL25435570 0.81 HDAC3 (0.51) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL1128054 0.81 HDAC3 (0.48) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL14166796 0.81 HDAC3 (0.48) HDAC3PARP1HSD17B3ESR1ESR2
Iodide SCHEMBL10482528 0.79 HDAC3 (0.47) HDAC3PARP1HSD17B3ESR1ESR2
Hydrochloric Acid SCHEMBL507702 0.79 HDAC3 (0.47) HDAC3PARP1HSD17B3ESR1ESR2
Hydrochloric Acid SCHEMBL2111158 0.79 HDAC3 (0.47) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL14637926 0.79 HDAC3 (0.69) HDAC3PARP1HSD17B3ESR1ESR2
SCHEMBL1127776 0.78 HDAC3 (0.46) HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4829187-A COLORIMETRIC INDICATOR, EXPOSURE TO SUNLIGHT SHISEIDO COMPANY LTD. (JP) 1989-05-09 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed