Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29467780 | 0.94 | HSD17B10 (0.47) | HSD17B10CA1CA2CA7MEN1 | |
| SCHEMBL29467783 | 0.94 | HSD17B10 (0.47) | HSD17B10CA1CA2CA7MEN1 | |
| SCHEMBL29467781 | 0.94 | HSD17B10 (0.47) | HSD17B10CA1CA2CA7MEN1 | |
| SCHEMBL13943216 | 0.92 | HSD17B10 (0.52) | HSD17B10CA1CA2CA7MEN1 | |
| SCHEMBL28166513 | 0.88 | HSD17B10 (0.50) | HSD17B10MEN1KMT2ATDP1USP2 | |
| SCHEMBL32668689 | 0.85 | — | — | |
| SCHEMBL27352235 | 0.85 | CA1 (0.56) | HSD17B10CA1CA2CA7MEN1 | |
| SCHEMBL221149 | 0.85 | — | — | |
| SCHEMBL3263850 | 0.85 | — | — | |
| SCHEMBL475863 | 0.83 | CA1 (0.48) | HSD17B10CA1CA2CA7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847332-A | USING A VINYL-FUNCTIONAL ALCOHOL AS A PROPAGATOR FOR THE CATIONIC RING-OPENING POLYMERIZATION OF CYCLIC FORMALS; GRAFT AND COMB POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0291761-A2 | Terminally unsaturated macromolecular monomers of polylactones and copolymers thereof | THE B.F. GOODRICH COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |