SCHEMBL10489686

SCHEMBL10489686

CCOC(=O)Nc1nc2cccc(C)c2c(=O)o1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.64
CTRB1 P17538 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10362992 0.85 ELANE (0.67) ELANECTRB1
SCHEMBL10362877 0.80 ELANE (0.67) ELANECTRB1
SCHEMBL10362713 0.79 ELANE (0.63) ELANECTRB1
SCHEMBL6504112 0.79 ELANE (1.00) ELANECTRB1
SCHEMBL10749700 0.77 ELANE (0.64) ELANECTRB1
SCHEMBL10362711 0.77 ELANE (1.00) ELANECTRB1
SCHEMBL27477974 0.77 ELANE (0.74) ELANECTRB1
SCHEMBL27495729 0.77 ELANE (0.74) ELANECTRB1
SCHEMBL27477973 0.77 ELANE (0.74) ELANECTRB1
SCHEMBL27495341 0.76 ELANE (0.72) ELANECTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4873232-A ARTHRITIS AND AUTOIMMUNE DISEASES SYNTEX (US) 1989-10-10 US disclosed