SCHEMBL10489986

SCHEMBL10489986

CCc1cc(S(=O)(=O)O)c(N)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA3 P07451 2/20 0.43
CA4 P22748 2/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
ALDH1A1 P00352 6/20 0.42
CTDSP1 Q9GZU7 1/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 2/20 0.38
CYP3A4 P08684 2/20 0.38
CASP1 P29466 2/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2468560 0.93 CA12 (0.39) CA12CA1CA2CA3CA4
SCHEMBL9350747 0.91 CA12 (0.38) CA12CA1CA2CA3CA4
SCHEMBL11859022 0.83 GRIN2D (0.40) CA12CA1CA2CA3CA4
SCHEMBL8213587 0.83 CTDSP1 (0.41) CA2ALDH1A1CTDSP1HSD17B10HPGD
SCHEMBL7756170 0.83 CTDSP1 (0.41) CA12CA1CA2CA3CA4
SCHEMBL30557456 0.81 CA1 (0.52) CA12CA1CA2CA3CA4
SCHEMBL1733790 0.81 CA1 (0.52) CA12CA1CA2CA3CA4
SCHEMBL10400528 0.79 CA1 (0.50) CA12CA1CA2CA3CA4
SCHEMBL9327065 0.79 CA1 (0.61) CA12CA1CA2CA3CA4
SCHEMBL7029578 0.79 GAA (0.52) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4810302-A STORAGE STABLE MIXTURES TOYO INK MANUFACTURING CO., LTD. (JP) 1989-03-07 US disclosed
US-4469515-A Production of pigments CIBA-GEIGY CORPORATION (US) 1984-09-04 US disclosed